Products

Oncology & Pharmacogenomic Assays

With patented Switchblocker™ and PrimerSwitch™ technologies, Tsunami and Riptide assays deliver high sensitivity and accuracy for demanding applications.

Oncology Assays- Tsunami EGFR

Less expensive and faster than NGS, Tsunami™ assays are a good choice when fast answers are critical. With 10X higher sensitivity than NGS, your  team will likely also report fewer QNS results. 

Tsunami oncology assays are:

  • Easy to use 
  • Compatible with most PCR instrument platforms. 
  • Deliver high sensitivity (0.1% MAF)

Specifications/Requirements: 

  • Fluorochromes/Detection: VIC (JOE/HEX), FAM, ROX, Cy5
  • Assays per tube: 24
  • Positive Controls: Not included
  • Cycles recommended: 39
  • NA: column or magnetic purification, 5ul sample per reaction
  • Reaction volume: 10ul

Targets: 

EGFR Del 19, EGFR L858, EGFR T790M, Pan Assay Control

Research Use Only, Not intended for Diagnostics, Not Approved by FDA

Pharmacogenomic Assays- RipTide

Riptide™ pharmacogenomic assays are developed from pharmacuetical guidelines and are correlated to genes that regulate or impact compound effectiveness including:

  • Statins
  • Lisinopril
  • Levothyroxine
  • Amlodipine

Riptide assays are:

  • Easy to use
  • Compatible with most PCR instrument platforms. 
  • Deliver high sensitivity (0.1% MAF)

Specifications/Requirements: 

  • Fluorochromes/Detection: VIC (JOE/HEX), FAM, ROX
  • Assays per tube: 48, 96, 200
  • Positive Controls: Included
  • Cycles recommended: 40
  • NA: column or magnetic purification, 5ul sample per reaction
  • Reaction volume: 10ul

Targets:

Gene Compound Note
SLCO1B1 & ABCG2 Statins CPIC A/B
ACE2 I/D intron 16 rs4646994 Lisinopril
DIO2 Levothyroxine
CYP3A5 (c.219-237A>G) Amlodipine, Levothyroxine

Research Use Only, Not intended for Diagnostics, Not Approved by FDA

Ready to Screen Rare DNA Mutations?

Aegea Products Frequently Asked Questions (FAQs)

What products and services does Aegea offer?

Aegea provides a range of products and services, including research-use-only (RUO) kits, and custom assay development. These offerings are designed to integrate seamlessly into existing laboratory workflows, enhancing the sensitivity and specificity of molecular analyses.

Who can benefit from Aegea’s technologies?

Aegea’s solutions are tailored for a diverse clientele, including pharmaceutical and biotech companies, life science researchers, and clinical laboratories developing new technologies and assays for DNA mutation detection. Organizations seeking to improve the detection of rare genetic events or to develop multiplexed assays will find Aegea’s technologies particularly advantageous. ​

Does Aegea offer custom assay development?

Yes. Aegea collaborates with clients to develop custom assays and adapt its technologies to various platforms. This collaborative approach ensures that the assays meet specific research or clinical needs. ​

How can I initiate a collaboration with Aegea?

To explore collaboration opportunities, you can contact us here LINK. We welcome partnerships that aim to advance molecular diagnostics and personalized medicine.

What distinguishes Aegea from other life science companies?

Best-in-class Switch-Blocker technology is unmatched in analytic sensitivity for rare DNA mutation detection. The company owns a suite of nucleic acid amplification technologies and a robust portfolio of 11 issued U.S. patents, and a proven track record in clinical research and validation.